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H-9 hydrochloride

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Formula: C11H13N3O2S.HCl
CAS: 116970-50-4
search Element: hydrochloride

Identification

Structural Formula
H-9 hydrochloride
CAS:
116970-50-4
EINECS:
Molecular Formula:
C11H13N3O2S.HCl
MDL:
MFCD00083242
SMILES:
C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN.Cl
Synonym:
rhoh9 ; mgc61427 ; g protein-coupled receptor 50 ; melatonin-related receptor ; arhc ; rhoc, his tagged human ; h-9 ; arh9 ; gpr50 ; mgc1448


Description

H-9 hydrochloride inhibits PKA (Ki=1.9 μM), PKC (Ki=18 μM; cGKI (PKG) =0.87 μM; MLCK=70 μM). It has shown to dramatically reduce the GABA response of GABAA currents in retinal rod bipolar cells as well as inhibit smooth muscle cell relaxation induced by cGRP. H-9 dihydrochloride has also been used for purification of protein kinases in ligand affinity chromatography.


Suppliers

Santa Cruz Biotechnology, Inc.
200553
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Prices & Availability




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Properties for H-9 hydrochloride

Molecular Weight:
287.77 g·mol−1
Melting point:
250-255 °C (dec)
Boiling point:
479.8° C at 760 mmHg
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R61 - May cause harm to the unborn child
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
Xi, Xn, T
Hazard symbol T Hazard symbol Xn Hazard symbol Xi
Storage temperature :
Refrigerator
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Alternative Distributors of [H-9 hydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

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MSDS:
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