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4-Phenylbutyric acid

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Formula: C10H12O2
CAS: 1821-12-1
search Element: phenylbutyric acid

Identification

Structural Formula
4-Phenylbutyric acid
CAS:
1821-12-1
EINECS:
217-341-8
Molecular Formula:
C10H12O2
MDL:
MFCD00004403
SMILES:
C1=CC=C(C=C1)CCCC(=O)O
Synonym:
phenylbutyric acid ; nsc 295 ; akos bbs-00003749 ; benzenebutyric acid ; timtec-bb sbb008452 ; 4-phenybutytic acid ; 4-benzene acid ; benzenebutanoicacid ; rarechem al bo 0178 ; buphenyl


Description

4-Phenylbutyric acid is a chemical chaperone, which suppresses oxidative stress by attenuating endoplasmic reticulum stress. 4-Phenylbutyric acid increases the expression of type 2 deiodinase (D2), via the accumulation of Dio2 mRNA. Studies indicate that 4-Phenylbutyric acid affects genes such as Ucp-1, Ucp-3 and Pgc-1α in a D2-dependent manner. The activation of these genes is thought to increase T3 production. Diabetic studies conducted on mice suggest that 4-Phenylbutyric acid normalizes serum glucose levels.


Suppliers

Shandong SanYoung Industry Co., Ltd
SSI14005600
Chemlyte Solutions
CS7202160
Autech Industry Co.,Limited
AIC10804320
Zhejiang Jiasi Chemical Co., Ltd.
ZJC13205280
Seqens International SAS
SIS9603840
Richman Chemical Inc.,
RCI8803520
Xiamen Equation Chemical Co.,Ltd
XECC12806400
Merck Schuchardt OHG
MSO8003200
AK Scientific, Inc.
AS7602280
Simagchem Corporation
SC8402520
Xingrui Industry Co., Limited
XIL11604640
Santa Cruz Biotechnology, Inc.
232961
Chemos GmbH & Co. KG
CC8002400
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Angene International Limited
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Dayang Chem (Hangzhou) Co.,Ltd.
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Ambeed, Inc.
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CSNpharm, Inc.
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BLD Pharmatech Ltd
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Prices & Availability




Data is processed


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Properties for 4-Phenylbutyric acid

Molecular Weight:
164.2 g·mol−1
Melting point:
49-51 °C(lit.)
Boiling point:
165 °C10 mm Hg(lit.)
Flash point:
>230 ºF
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
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Alternative Distributors of [4-Phenylbutyric acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Chembay Co., Ltd. | Molekula GmbH | Suzhou Yuanfang Chemical Co., Ltd. | Pratap Organics | LianYunGang Chiral Chemical(China)CO.,LTD  | ABCR GmbH & Co. KG | Lemandou Chemicals Co., Ltd. | Frinton Laboratories | TCI Europe NV | Chemwill Asia Co.,Limited | Shanghai ChemVia Co., Ltd | Ubichem PLC | Share Chemical Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Suchem Pharma Co., Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Ningbo Samreal Chemical Co., Ltd. | Shanghai Hanhong Chemical Co., Ltd. | Zhejiang Sanhe Pharmachem Co., Ltd. | Junwee Chemical Co., Ltd. | AOKBIO Co., Ltd. | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | King Tang Chemical Group Industry Co., Ltd. | Watson International Ltd | BOC Sciences | Scandinavian Formulas, Inc. | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Pfaltz & Bauer, Inc. | Xiamen Hisunny Chemical Co., Ltd. | Insight High Technology Co., Ltd. | Clearsynth Canada INC. | Haihang Industry Co., Ltd.

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