Wee1 Inhibitor II | CAS 622855-50-9

Element: inhibitor wee1

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C-S » Chemicals » wee-inhibitor-PX87673

Identification

Wee1 Inhibitor II

CAS:

622855-50-9

EINECS:

Molecular Formula:

C₂₄H₁₉ClN₂O₃

MDL:

SMILES:

CCCCN1C2=C(C=C(C=C2)O)C3=C1C=C(C4=C3C(=O)NC4=O)C5=CC=CC=C5Cl

Synonym:

Pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione, 6-butyl-4-(2-chlorophenyl)-9-hydroxy-

Description

Wee1 Inhibitor II is a pyrrolocarbazole compound that act as a potent, ATP-binding site-targeting inhibitor of Wee1 (IC₅₀ = 59 nM) with a ~590-fold selectivity over the related checkpoint kinase Chk1 (IC₅₀ = 35 μM).

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Santa Cruz Biotechnology, Inc.

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Properties for Wee1 Inhibitor II

Molecular Weight:

418.9 g·mol−1

Solubility:

Soluble in DMSO (10 mg/ml), and ethanol (10 mg/ml).

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Alternative Distributors of [Wee1 Inhibitor II]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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